Sanford Guide Integration
Sanford Guide gives prescribers the information they need to make the right choice for their patients.
Since clinicians know their patients, our goal is to present all targeted data identified in the laboratory results to assist the clinician in making the right choice. Sanford Guide gives prescribers concise clinical guidelines that allow patient history, symptoms, allergies, resistance patterns, and other factors to be taken into consideration before selecting an antimicrobial regimen.
Using Sanford Guide facilitates antimicrobial stewardship and improves patient outcomes by giving prescribers several treatment options based on the clinical scenario.
Provides effective, efficient, and responsible guidance
Includes comprehensive yet concise information that is easy to follow
Avoids oversimplification by providing targeted options for treatment
Allows for consideration of patient-specific factors to prescribe based on the infection suspected and the organisms isolated
Is interactive, allowing prescribers to get targeted information with one click
Aligns with recommendations to improve antibiotic prescribing through use of nationally recognized guidelines
Curated by an editorial board of infectious diseases experts
Has been trusted for over 50 years to assist the prescribing of antimicrobial therapy
How it Works
Treatment recommendations for detected pathogens and pertinent syndromes are seamlessly presented within the lab report. Prescribers can then deep dive into comprehensive drug information and related topics using an online portal. Sanford Guide empowers clinicians with the resources needed to make decisions efficiently and with confidence, which in turn saves time, saves money, and improves patient outcomes.
Why it Matters
Infectious diseases diagnostics are constantly evolving with increasing levels of complexity.
Due to a lack of knowledge of the sensitivity, specificity, and predictive value of newer molecular tests, providers may not have the confidence to interpret the results. The identification of organisms at an increasingly specific species-level along with multiple positive results of unknown clinical significance can be confusing and may lead to inappropriate treatment and unnecessary testing. [2-6]
The complications associated with inappropriate treatment include antibiotic resistance, adverse events, poor outcomes, and increased healthcare costs.  Recent reports have described increasing drug-resistant infections particularly in community settings.  Additionally, antibiotic adverse effects result in over 145,000 emergency department visits per year for adults.  Other complications include Clostridioides difficile infection with more than 12,000 deaths per year.  Optimizing antibiotic use is a public health priority, and improving antibiotic prescribing is one way to slow antibiotic resistance. [7-8, 10]
How Do We Get It?
Whether you want to sign up for a new LIS, incorporate pre-designed reports into your existing platform, or build a custom solution using our API, we have a solution for you.
- Clinical setting, primary and alternative regimens (often in consideration of resistance detected), and antimicrobial stewardship considerations
- Additional information regarding treatment of special populations such as pregnancy
- Clinical setting, classification, antimicrobial spectrum, primary and alternative regimens, considerations for resistance, antimicrobial stewardship considerations, and other information to guide therapy selection
- Adult dose, pediatric dose, renal and hepatic dose adjustment, dose adjustments based on other factors, adverse effects, spectrum, comprehensive pharmacology information, and drug interactions
- Morjaria S, Chapin KC. Who to test, when, and for what: why diagnostic stewardship in infectious diseases matters. J Mol Diagn. 2020;22(9):1109-1113.
- Messacar K, Parker SK, Todd JK, et al. Implementation of rapid molecular infectious disease diagnostics: the role of diagnostic and antimicrobial stewardship. J Clin Microbiol. 2017;55(3):715-723.
- Bard JD, McElvania E. Panels and syndromic testing in clinical microbiology. Clin Lab Med. 2020;40(4):393-420.
- Ramanan P, Bryson AL, Binnicker MJ, et al. Syndromic panel-based testing in clinical microbiology. Clin Microbiol Rev. 2017;31(1): e00024-17. doi: 10.1128/ CMR.00024-17.
- Wojno KJ, Baunock D, Luke N, et al. Multiplex PCR based urinary tract infection (UTI) analysis compared to traditional urine culture in identifying significant pathogens in symptomatic patients. Urology. 2020;136:119-126.
- Xu R, Deebel N, Casals R, et al. A new gold rush: a review of current and developing diagnostic tools for urinary tract infections. Diagnostics. 2021;11(3): 479; https://doi.org/10.3390/diagnostics11030479
- CDC. Improving outpatient antibiotic prescribing: a toolkit for healthcare payers. Atlanta, GA: US Department of Health and Human Services, CDC; 2021.
CDC. Antibiotic resistance threats in the United States, 2019. Atlanta, GA: US Department of Health and Human Services, CDC; 2019.
- Geller AI, Lovegrove MC, Shehab N, Hicks LA, Sapiano MRP, Budnitz DS. National Estimates of Emergency Department Visits for Antibiotic Adverse Events Among Adults-United States, 2011-2015. J Gen Intern Med. 2018;33(7):1060-1068. doi:10.1007/s11606-018-4430-x
- Sanchez GV, Fleming-Dutra KE, Roberts RM, Hicks LA. Core elements of outpatient antibiotic stewardship. MMWR Recomm Rep. 2016;65(No.RR-6):1-12.
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